From Slashdot. Rather interesting. Basically they say that the mouse precision and menu lag are worse in Vista then they were in XP, which has a negative impact on productivity. From my usage of Vista I can concur. I even turned off the eye candy relating to the mouse cursor and menus and it still seems slower then XP. They claim Mac OS X is far superior in both categories.
It would seem poor mouse accuracy would be a hindrance in games, unless that only applies to the desktop and not when you are in a DirectX environment. It would seem that the whole Aero/Glass thing would blur the line between desktop and DirectX tough. . . . Combine poor mouse accuracy with DirectX10 being exclusive to Vista and that is yet another reason for game developers not to support it.